TIFA
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
FITC
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS with 0.09 % (W/V) sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
抗原
TIFA
(TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))
别名
TIFA / T2BP
背景
Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.Synonyms: Putative MAPK-activating protein PM14, Putative NF-kappa-B-activating protein 20, TRAF-interacting protein with FHA domain-containing protein A, TRAF2-binding protein