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TGIF1 抗体 (Middle Region)

This anti-TGIF1 antibody is a 兔 多克隆 antibody detecting TGIF1 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN955179
发货至: 中国

Quick Overview for TGIF1 抗体 (Middle Region) (ABIN955179)

抗原

See all TGIF1 抗体
TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

适用

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人, 小鼠

宿主

  • 31
  • 6
  • 1

克隆类型

  • 33
  • 5
多克隆

标记

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This TGIF1 antibody is un-conjugated

应用范围

  • 30
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  • 5
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  • 1
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 9
    • 7
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    • 3
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    • 2
    • 2
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    • 1
    • 1
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    AA 215-245, Middle Region

    特异性

    This antibody detects TGIF1 (Center).

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    免疫原

    KLH conjugated synthetic peptide between 215-245 amino acids from the Central region of human TGIF1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原

    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

    别名

    TGIF1

    背景

    The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.Synonyms: 5'-TG-3'-interacting factor 1, Homeobox protein TGIF1, TGIF

    基因ID

    7050

    NCBI登录号

    NP_003235

    途径

    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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