Transferrin Receptor 2 抗体 (C-Term)
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- 抗原 See all Transferrin Receptor 2 (TFR2) 抗体
- Transferrin Receptor 2 (TFR2)
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抗原表位
- AA 673-703, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Transferrin Receptor 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects Human TFR2 (C-term). Other species not tested.
- 纯化方法
- Protein A column followed by peptide affinity purification
- 免疫原
- KLH conjugated synthetic peptide between 673-703 amino acids from the C-terminal region of human TFR2
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TFR2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS, 0.09 % (W/V) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- 抗原
- Transferrin Receptor 2 (TFR2)
- 别名
- TFR2 (TFR2 产品)
- 别名
- TFR2 antibody, Trfr2 antibody, HFE3 antibody, TFRC2 antibody, zgc:123043 antibody, transferrin receptor 2 antibody, TFR2 antibody, Tfr2 antibody, tfr2 antibody
- 背景
- This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Function: Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Cellular Location: Cell membrane, Single-pass type II membrane protein. Tissue Location: Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly.Synonyms: Transferrin receptor protein 2
- 分子量
- 88755 Da (Calculated)
- 基因ID
- 7036
- NCBI登录号
- NP_001193784
- 途径
- Transition Metal Ion Homeostasis
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