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Transferrin Receptor 2 抗体 (C-Term)

This anti-Transferrin Receptor 2 antibody is a 兔 多克隆 antibody detecting Transferrin Receptor 2 in WB 和 EIA. Suitable for 人.
产品编号 ABIN955173
发货至: 中国

Quick Overview for Transferrin Receptor 2 抗体 (C-Term) (ABIN955173)

抗原

See all Transferrin Receptor 2 (TFR2) 抗体
Transferrin Receptor 2 (TFR2)

适用

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宿主

  • 46
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克隆类型

  • 37
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多克隆

标记

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This Transferrin Receptor 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 5
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    AA 673-703, C-Term

    特异性

    This antibody detects Human TFR2 (C-term). Other species not tested.

    纯化方法

    Protein A column followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 673-703 amino acids from the C-terminal region of human TFR2

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % (W/V) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原

    Transferrin Receptor 2 (TFR2)

    别名

    TFR2

    背景

    This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Function: Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Cellular Location: Cell membrane, Single-pass type II membrane protein. Tissue Location: Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly.Synonyms: Transferrin receptor protein 2

    分子量

    88755 Da (Calculated)

    基因ID

    7036

    NCBI登录号

    NP_001193784

    途径

    Transition Metal Ion Homeostasis
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