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STK38 抗体 (AA 365-466)

This anti-STK38 antibody is a 小鼠 单克隆 antibody detecting STK38 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN954986
发货至: 中国

Quick Overview for STK38 抗体 (AA 365-466) (ABIN954986)

抗原

See all STK38 抗体
STK38 (serine/threonine Kinase 38 (STK38))

适用

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  • 1
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 44
  • 7
  • 1
小鼠

克隆类型

  • 46
  • 6
单克隆

标记

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  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This STK38 antibody is un-conjugated

应用范围

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  • 30
  • 13
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  • 7
  • 5
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

克隆位点

6F1
  • 抗原表位

    • 15
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 365-466

    特异性

    Recognizes STK38

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Protein A Chromatography

    免疫原

    STK38 (AAH12085, 365 a.a. ~ 466 a.a) partial recombinant protein with GST tag.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.2

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    STK38 (serine/threonine Kinase 38 (STK38))

    别名

    STK38

    背景

    STK38 contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.Synonyms: NDR1, Nuclear Dbf2-related kinase 1, Serine/threonine-protein kinase 38

    基因ID

    11329

    NCBI登录号

    NP_009202

    UniProt

    Q15208
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