STK38 抗体 (AA 365-466)
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Quick Overview for STK38 抗体 (AA 365-466) (ABIN954986)
抗原
See all STK38 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 365-466
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特异性
- Recognizes STK38
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Protein A Chromatography
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免疫原
- STK38 (AAH12085, 365 a.a. ~ 466 a.a) partial recombinant protein with GST tag.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- STK38 (serine/threonine Kinase 38 (STK38))
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别名
- STK38
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背景
- STK38 contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.Synonyms: NDR1, Nuclear Dbf2-related kinase 1, Serine/threonine-protein kinase 38
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基因ID
- 11329
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NCBI登录号
- NP_009202
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UniProt
- Q15208
抗原
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