SPG20 抗体 (C-Term)
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北京 101111
Quick Overview for SPG20 抗体 (C-Term) (ABIN954907)
抗原
See all SPG20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 490-519, C-Term
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特异性
- This antibody recognizes Human
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 490-519 amino acids from the C-terminal region of Human SPG20 Genename: SPG20
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
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别名
- Spartin / SPG20
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背景
- SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome)Synonyms: KIAA0610, Spastic paraplegia 20 protein, TAHCCP1, Trans-activated by hepatitis C virus core protein 1
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分子量
- 72833 Da
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基因ID
- 23111
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NCBI登录号
- NP_001135766
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途径
- Regulation of Cell Size, SARS-CoV-2 Protein Interactome
抗原
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