SNX15 抗体 (C-Term)
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Quick Overview for SNX15 抗体 (C-Term) (ABIN954886)
抗原
See all SNX15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 222-251, C-Term
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特异性
- This antibody detects human SNX15 at C-term.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Purified through a protein A column; followed by peptide affinity purification.
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region ( between 222-251aa) of human SNX15.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SNX15 (Sorting Nexin 15 (SNX15))
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别名
- Sorting Nexin-15 (SNX15)
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背景
- The SNX15 gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms.
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基因ID
- 29907
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NCBI登录号
- NP_037438
抗原
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