SNX13 抗体 (C-Term)
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Quick Overview for SNX13 抗体 (C-Term) (ABIN954885)
抗原
See all SNX13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 779-807, C-Term
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特异性
- This antibody detects human SNX13 at C-term.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Purified through a protein A column; followed by peptide affinity purification.
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 779-807aa) of human Sorting nexin-13 (SNX13).
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SNX13 (Sorting Nexin 13 (SNX13))
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别名
- Sorting Nexin-13 (SNX13)
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背景
- SNX13 gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.Synonyms: KIAA0713, RGS domain- and PHOX domain-containing protein
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基因ID
- 23161
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NCBI登录号
- NP_055947
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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