SORD 抗体 (Middle Region)
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Quick Overview for SORD 抗体 (Middle Region) (ABIN954884)
抗原
See all SORD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 210-239, Middle Region
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特异性
- This antibody recognizes Human SORD (Center).
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of Human SORD. Genename: SORD
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SORD (Sorbitol Dehydrogenase (SORD))
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别名
- SORD
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背景
- Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor. Synonyms: L-iditol 2-dehydrogenase, Sorbitol dehydrogenase
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分子量
- 38325 Da
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基因ID
- 6652
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NCBI登录号
- NP_003095
抗原
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