SH3PXD2A
适用: 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy7
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS, 0.09 % (W/V) Sodium Azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
抗原
SH3PXD2A
(SH3 and PX Domains 2A (SH3PXD2A))
别名
SH3PXD2A
背景
SH3PXD2A is required for podosome formation, degradation of the extracellular matrix, and for the invasiveness of some cancer cells. Binds phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,4-biphosphate (PtdIns(3,4)P2). In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.Synonyms: Adaptor protein TKS5, FISH, Five SH3 domain-containing protein, KIAA0418, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, SH3MD1, TKS5