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SAR1B 抗体 (Middle Region)

This anti-SAR1B antibody is a 兔 多克隆 antibody detecting SAR1B in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN954670
发货至: 中国

Quick Overview for SAR1B 抗体 (Middle Region) (ABIN954670)

抗原

See all SAR1B 抗体
SAR1B (SAR1 Homolog B (SAR1B))

适用

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宿主

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克隆类型

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多克隆

标记

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This SAR1B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 96-124, Middle Region

    特异性

    Recognizes SAR1B (Center).

    纯化方法

    Protein A column followed by peptide Affinity purification

    免疫原

    KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of Human SAR1B Genename: SAR1B

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SAR1B (SAR1 Homolog B (SAR1B))

    别名

    SAR1B

    背景

    SAR1B belongs to the small GTPase superfamily, SAR1 family. It is involved in transport from the endoplasmic reticulum to the Golgi apparatus and is activated by the guanine nucleotide exchange factor PREB. SAR1B is involved in the selection of the protein cargo and the assembly of the COPII coat complex. Defects in SAR1B are the cause of chylomicron retention disease (CMRD). CMRD is an autosomal recessive disorder of severe fat malabsorption associated with failure to thrive in infancy. The conditions are characterized by deficiency of fat-soluble vitamins, low blood cholesterol levels, and a selective absence of chylomicrons from blood. Affected individuals accumulate chylomicron-like particles in membrane-bound compartments of enterocytes, which contain large cytosolic lipid droplets. Cellular localization: Endoplasmic reticulum membrane, Peripheral membrane protein. Golgi apparatus, Golgi stack membrane, Peripheral membrane protein. Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.Synonyms: GTBPB, GTP-binding protein SAR1b, SAR1B, SARA2, SARB

    基因ID

    51128

    NCBI登录号

    NP_001028675

    途径

    Lipid Metabolism
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