S100B 抗体 (Middle Region)
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北京 101111
Quick Overview for S100B 抗体 (Middle Region) (ABIN954658)
抗原
See all S100B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-56, Middle Region
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特异性
- Recognizes human S100B (center). Other species not tested.
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纯化方法
- Protein A column followed by peptide Affinity purification
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免疫原
- KLH conjugated synthetic peptide between 27-56 amino acids from the Central region of Human S100B/S-100. Genename: S100B
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- S100B (S100 Calcium Binding Protein B (S100B))
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别名
- S100B
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背景
- The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.Synonyms: Astrocyte Marker, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 beta, S100 calcium-binding protein B
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基因ID
- 6285
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NCBI登录号
- NP_006263
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途径
- Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
抗原
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