RUNX3 抗体 (Middle Region)
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北京 101111
Quick Overview for RUNX3 抗体 (Middle Region) (ABIN954644)
抗原
See all RUNX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 167-197, Middle Region
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纯化方法
- Protein A column followed by peptide Affinity purification
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免疫原
- KLH conjugated synthetic peptide between 167-197 amino acids from the Central region of Human RUNX3 Genename: RUNX3
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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别名
- RUNX3
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背景
- This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: AML2, Acute myeloid leukemia 2 protein, CBF-alpha-3, CBFA3, Core-binding factor subunit alpha-3, Oncogene AML-2, PEA2-alpha C, PEBP2-alpha C, PEBP2A3, Polyomavirus enhancer-binding protein 2 alpha C subunit, Runt-related transcription factor 3, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit
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基因ID
- 864
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NCBI登录号
- NP_001026850
抗原
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