PCGF2 抗体 (Middle Region)
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北京 101111
Quick Overview for PCGF2 抗体 (Middle Region) (ABIN954565)
抗原
See all PCGF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-150, Middle Region
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特异性
- This antibody recognizes RNF110 / PCGF2.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Purified through a Protein A column followed by peptide affinity purification
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 120-150aa) of human RNF110 / PCGF2.
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亚型
- Ig Fraction
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anti-Polycomb Group Ring Finger 2 (PCGF2) (AA 236-294) antibody
PCGF2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D6 unconjugated
anti-Polycomb Group Ring Finger 2 (PCGF2) (AA 170-210) antibodyPCGF2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 2 (PCGF2) (C-Term) antibodyVerified PCGF2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 2 (PCGF2) (AA 103-316) antibodyPCGF2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
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别名
- RNF110 / PCGF2
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背景
- The Polycomb group RING finger protein 2 encoded by the PCGF2 gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.Synonyms: DNA-binding protein Mel-18, MEL18, PCGF2, Polycomb group RING finger protein 2, RING finger protein 110, RNF110, ZNF144, Zinc finger protein 144
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基因ID
- 7703
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NCBI登录号
- NP_009075
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途径
- Chromatin Binding
抗原
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