RBM5 抗体 (N-Term)
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北京 101111
Quick Overview for RBM5 抗体 (N-Term) (ABIN954485)
抗原
See all RBM5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 17-46, N-Term
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特异性
- This antibody recognizes Human RBM5 (N-term).
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of Human RBM5. Genename: RBM5
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RBM5 (RNA Binding Motif Protein 5 (RBM5))
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别名
- RBM5 / LUCA15
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背景
- Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosisSynonyms: NY-REN-9, Putative tumor suppressor LUCA15, RNA-binding motif protein 5, RNA-binding protein 5, Renal carcinoma antigen NY-REN-9
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分子量
- 92154 Da
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基因ID
- 10181
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NCBI登录号
- NP_005769
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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