PC 抗体 (N-Term)
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Quick Overview for PC 抗体 (N-Term) (ABIN954396)
抗原
See all PC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 52-82, N-Term
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特异性
- This antibody reacts to PC.
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交叉反应 (详细)
- Species reactivity (tested):Mouse.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human PC
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PC (Pyruvate Carboxylase (PC))
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别名
- Pyruvic Carboxylase (PC)
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背景
- This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].Synonyms: PCB, Pyruvate carboxylase mitochondrial
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基因ID
- 5091
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NCBI登录号
- NP_000911
抗原
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