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PC 抗体 (N-Term)

The 兔 多克隆 anti-PC antibody (ABIN954396) specifically detects PC in WB, IHC (p) 和 EIA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN954396
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PC 抗体 (N-Term) (ABIN954396)

抗原

See all PC 抗体
PC (Pyruvate Carboxylase (PC))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 52-82, N-Term

    特异性

    This antibody reacts to PC.

    交叉反应 (详细)

    Species reactivity (tested):Mouse.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human PC

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PC (Pyruvate Carboxylase (PC))

    别名

    Pyruvic Carboxylase (PC)

    背景

    This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].Synonyms: PCB, Pyruvate carboxylase mitochondrial

    基因ID

    5091

    NCBI登录号

    NP_000911
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