PITRM1 抗体 (Middle Region)
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北京 101111
Quick Overview for PITRM1 抗体 (Middle Region) (ABIN954153)
抗原
See all PITRM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 497-526, Middle Region
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 497-526 amino acids from the Central region of human PITRM1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))
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别名
- PITRM1
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背景
- ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.Synonyms: KIAA1104, MP1, Metalloprotease 1, Pitrilysin metalloproteinase 1, Presequence protease mitochondrial
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分子量
- 117455 Da
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基因ID
- 9606
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途径
- PI3K-Akt Signaling, SARS-CoV-2 Protein Interactome
抗原
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