NDAP antibody, 2510012P17Rik antibody, 4930534E15Rik antibody, CGI-06 antibody, Ndap7 antibody, phosphatidylinositol glycan anchor biosynthesis class T L homeolog antibody, phosphatidylinositol glycan anchor biosynthesis class T antibody, phosphatidylinositol glycan anchor biosynthesis, class T antibody, pigt.L antibody, PIGT antibody, Pigt antibody
背景
The PIGT gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Several transcript variants encoding different isoforms have been found for this gene.Synonyms: CGI-06, GPI transamidase component PIG-T, PIG-T, PSEC0, Phosphatidylinositol-glycan biosynthesis class T protein