PEG10
适用: 人, 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy5.5
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS containing 0.09 % (W/V) Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
PEG10
(Paternally Expressed 10 (PEG10))
别名
PEG10
背景
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.Synonyms: EDR, Embryonal carcinoma differentiation-regulated protein, KIAA1051, MAR2, MART2, MEF3-like protein 1, MEF3L1, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, Paternally expressed gene 10 protein, RGAG3, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Retrotransposon-derived protein PEG10, Ty3/Gypsy-like protein