PDZK1 抗体 (Middle Region)
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Quick Overview for PDZK1 抗体 (Middle Region) (ABIN954079)
抗原
See all PDZK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 195-224, Middle Region
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特异性
- This antibody recognizes Human PDZK1 (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 195-224 amino acids from the Central region of human PDZK1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PDZK1 (PDZ Domain Containing 1 (PDZK1))
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别名
- PDZD1
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背景
- A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).Synonyms: CAP70, NHE-RF3, NHERF-3, NHERF3, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, NaPi-Cap1, PDZ domain-containing protein 1, PDZK1, Sodium-hydrogen exchanger regulatory factor 3
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分子量
- 57129 Da
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基因ID
- 5174
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NCBI登录号
- NP_001188254
抗原
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