PDP 抗体 (Middle Region)
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Quick Overview for PDP 抗体 (Middle Region) (ABIN954075)
抗原
See all PDP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 366-395, Middle Region
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特异性
- This antibody recognizes Human PDP1 (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 366-395 amino acids from the Central region of Human PDP1
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亚型
- Ig Fraction
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anti-Pyruvate Dehydrogenase Phosphatase (PDP) antibody
KO Validated PDP 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 308-336) antibodyPDP 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB31327 unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 72-260) antibodyPDP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 1-154) antibodyPDP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) antibodyPDP 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 315-537) antibodyPDP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 821-850), (C-Term) antibodyPDP 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PDP (Pyruvate Dehydrogenase Phosphatase (PDP))
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别名
- PDP1
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背景
- Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported, one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: Mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, PDP, PDPC1, PPM2C, Protein phosphatase 2C, Pyruvate dehydrogenase phosphatase catalytic subunit 1
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分子量
- 61054 Da
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基因ID
- 54704
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NCBI登录号
- NP_001155250
抗原
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