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PDHA1 抗体 (Middle Region)

This anti-PDHA1 antibody is a 兔 多克隆 antibody detecting PDHA1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN954070
发货至: 中国
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PDHA1 抗体 (Middle Region) (ABIN954070)

抗原

See all PDHA1 抗体
PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PDHA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 233-263, Middle Region

    特异性

    This antibody recognizes Human PDHA1 (Center).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 233~263 amino acids from the Central region of Human PDHA1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

    别名

    PDHA1

    背景

    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome.Synonyms: PDHE1-A type I, PHE1A, Pyruvate dehydrogenase E1 component subunit alpha somatic form mitochondrial

    分子量

    43296 Da

    基因ID

    5160

    NCBI登录号

    NP_000275

    途径

    Warburg Effect
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