PDHA1 抗体 (Middle Region)
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Quick Overview for PDHA1 抗体 (Middle Region) (ABIN954070)
抗原
See all PDHA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 233-263, Middle Region
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特异性
- This antibody recognizes Human PDHA1 (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 233~263 amino acids from the Central region of Human PDHA1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
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别名
- PDHA1
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背景
- The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome.Synonyms: PDHE1-A type I, PHE1A, Pyruvate dehydrogenase E1 component subunit alpha somatic form mitochondrial
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分子量
- 43296 Da
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基因ID
- 5160
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NCBI登录号
- NP_000275
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途径
- Warburg Effect
抗原
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