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BTBD14A 抗体 (C-Term)

This 兔 多克隆 anti-BTBD14A antibody specifically detects BTBD14A in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN953595
发货至: 中国
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Quick Overview for BTBD14A 抗体 (C-Term) (ABIN953595)

抗原

See all BTBD14A 抗体
BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

适用

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宿主

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克隆类型

  • 34
多克隆

标记

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This BTBD14A antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 472-502, C-Term

    特异性

    This antibody recognizes Human NACC2 / BTBD14A (C-term).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 472-502 amino acids from the C-terminal region of human NACC2 / BTBD14A

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

    别名

    NACC2 / BTBD14A

    背景

    BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.Synonyms: BTB/POZ domain-containing protein 14A, Nucleus accumbens-associated protein 2

    分子量

    62837 Da

    基因ID

    138151

    NCBI登录号

    NP_653254

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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