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Myeloid Lineage 抗体 (PE)

The PE-conjugated 小鼠 单克隆 anti-Myeloid Lineage antibody (Clone OX-82) (ABIN953568) specifically detects Myeloid Lineage in FACS, IHC (fro) 和 WB. The antibody is reactive with 大鼠 samples.
产品编号 ABIN953568
发货至: 中国
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Quick Overview for Myeloid Lineage 抗体 (PE) (ABIN953568)

抗原

Myeloid Lineage

适用

大鼠

宿主

  • 3
小鼠

克隆类型

  • 3
单克隆

标记

  • 1
  • 1
  • 1
PE

应用范围

Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)

克隆位点

OX-82
  • 交叉反应 (详细)

    Species reactivity (tested):Rat.

    纯化方法

    Protein G Chromatography of Ascites fluid.

    免疫原

    Anemic Rat bone marrow.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE! This product is photosensitive and should be protected from light.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    Myeloid Lineage

    背景

    Hematopoietic stem cells (HSC) are the precursor cells found in the bone marrow which give rise to all the blood cell types of both the Myeloid and lymphoid lineages, which include monocytes and macrophages, neutrophils, basophils, eosinophils, T cells, B cells, NK cells, microglia, erythrocytes, megakaryocytes and dendritic cells. During the process of hematopoiesis, Myeloid lineage cells originate from the bone marrow, while Lymphoid lineage cells originate from the lymph tissue. Blimp-1 is a key regulator of the differentiation of the separate hematopoietic myeloid and lymphoid lineages. The distinction between myeloid and lymphoid lineages is essential to diagnose and treat certain cancers. Myeloid lineage cells induce inflammatory cytokine production upon activation by Kaposi's sarcoma-associated herpesvirus OX2 glycoprotein. At the stage of myelocytes, Myeloid lineage cells express a substantial number of IL-8 receptor homologs.
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