MBP 抗体
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Quick Overview for MBP 抗体 (ABIN953563)
抗原
See all MBP 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for the ~18k & 22k myelin basic protein in Western blots of Rat brain homogenate.
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交叉反应 (详细)
- Species reactivity (tested):Human, Bovine, Mouse and Rat.
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纯化方法
- Ig Fraction
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免疫原
- Three peptide sequences conserved in higher vertebrate MBP proteins.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- MBP (Myelin Basic Protein (MBP))
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别名
- Myelin Basic Protein
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背景
- Myelin Basic Protein (MBP) is one of the major proteins of the myelin sheath surrounding axons in the nervous system. Since it is of relatively low molecular weight and high abundance the protein sequence was determined from purified protein over 30 years ago (Eylar et al., 1971). The protein is made by oligodendrocytes in the central nervous system, so antibodies to MBP are good markers of this cell type. However, transcripts from the same gene are also expressed in certain hematopoetic lineage cells (Marty et al., 2002). In the central nervous system there are there different forms of the protein made by alternate transcription from a single gene, which have molecular weights of 21.5, 18.5, and 17.2 kDa. Since the two lower molecular weight forms are very close in molecular size, MBP antibodies typically show two bands on Western blots, one at about 22 kDa and another at about 18 kDa.Synonyms: MBP, Myelin membrane encephalitogenic protein
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基因ID
- 4155
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NCBI登录号
- NP_001020252
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UniProt
- P02686
抗原
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