MYBPC3 抗体 (N-Term)
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Quick Overview for MYBPC3 抗体 (N-Term) (ABIN953556)
抗原
See all MYBPC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 188-218, N-Term
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特异性
- This antibody recognizes MYBPC3 at N-term.
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交叉反应 (详细)
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Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse. -
纯化方法
- Purified through a Protein A column followed by peptide affinity purification
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 188-218aa) of human MYBPC3.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
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别名
- MYBPC3
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背景
- MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.Synonyms: C-protein cardiac muscle isoform, cardiac-type Myosin-binding protein C
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基因ID
- 4607
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NCBI登录号
- NP_000247
抗原
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