MXI1 抗体 (Middle Region)
Quick Overview for MXI1 抗体 (Middle Region) (ABIN953554)
抗原
See all MXI1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 52-82, Middle Region
-
特异性
- This antibody recognizes human and mouse MXI1.
-
纯化方法
- Purified through a Protein A column followed by peptide affinity purification
-
免疫原
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 52-82aa) of human MXI1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) Sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- MXI1 (MAX Interactor 1 (MXI1))
-
别名
- MXI1
-
背景
- Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.Synonyms: Class C basic helix-loop-helix protein 11, MAX-interacting protein 1, Max interactor 1, bHLHc11
-
分子量
- 26062 Da
-
基因ID
- 4601
-
NCBI登录号
- NP_005953
-
途径
- Maintenance of Protein Location
抗原
-