Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS with 0.09 % (W/V) Sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
MUL1
(Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
别名
MUL1 / RNF218
背景
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.Synonyms: C1orf166, E3 ubiquitin-protein ligase MUL1, GIDE, Growth inhibition and death E3 ligase, MAPL, MULAN, Mitochondrial ubiquitin ligase activator of NFKB 1, Mitochondrial-anchored protein ligase, Putative NF-kappa-B-activating protein 266, RING finger protein 218