MUL1 抗体 (C-Term)
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Quick Overview for MUL1 抗体 (C-Term) (ABIN953547)
抗原
See all MUL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 279-309, C-Term
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特异性
- This antibody recognizes MUL1 / RNF218 at C-term.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Purified through a Protein A column followed by peptide affinity purification
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 279-309aa) of human MUL1 / RNF218
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
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别名
- MUL1 / RNF218
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背景
- E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.Synonyms: C1orf166, E3 ubiquitin-protein ligase MUL1, GIDE, Growth inhibition and death E3 ligase, MAPL, MULAN, Mitochondrial ubiquitin ligase activator of NFKB 1, Mitochondrial-anchored protein ligase, Putative NF-kappa-B-activating protein 266, RING finger protein 218
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基因ID
- 79594
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NCBI登录号
- NP_078820
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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