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MRPS12 抗体 (Middle Region)

This anti-MRPS12 antibody is a 兔 多克隆 antibody detecting MRPS12 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN953516
发货至: 中国

Quick Overview for MRPS12 抗体 (Middle Region) (ABIN953516)

抗原

See all MRPS12 抗体
MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

适用

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宿主

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克隆类型

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多克隆

标记

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This MRPS12 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 35-67, Middle Region

    特异性

    This antibody recognizes Human MRPS12 (Center).

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 35-67 amino acids from the Central region of Human MRPS12 Genename: MRPS12

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

    别名

    MRPS12

    背景

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same proteinSynonyms: 28S ribosomal protein S12, MRP-S12, MT-RPS12, RPMS12, RPSM12, S12mt, mitochondrial

    基因ID

    6183

    NCBI登录号

    NP_066930

    途径

    Sensory Perception of Sound
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