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MPZ 抗体

This anti-MPZ antibody is a 小鸡 多克隆 antibody detecting MPZ in WB, IHC (p) 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN953494
发货至: 中国

Quick Overview for MPZ 抗体 (ABIN953494)

抗原

See all MPZ 抗体
MPZ (Myelin Protein Zero (MPZ))

适用

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人, 小鼠

宿主

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小鸡

克隆类型

  • 55
  • 9
多克隆

标记

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This MPZ antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 特异性

    Recognizes P0 Myelin Protein.

    纯化方法

    Affinity Chromatography using a peptide column.

    免疫原

    Two antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (NP_032649) and Human (NP_000521) gene products. Production: After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.2 mg/ml. Finally, equal volumes of both of these affinity purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized.

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted in the dark at 2-8 °C.
  • 抗原

    MPZ (Myelin Protein Zero (MPZ))

    别名

    MPZ

    背景

    Human Myelin Protein Zero (Po) is a 28,400 dalton protein (258 amino acids) found in myelin of the PNS, but not the CNS. Expressed in myelinating Schwann cells, Po serves as a homophilic adhesion molecule, allowing adjacent laminae of the myelin sheath to undergo compaction. Po is also a marker of a subpopulation of migrating neural crest cells. Mutations of the MPZ gene product in humans is responsible for Charcot-Marie-Tooth type 1B neuropathies (HMSN1B).Synonyms: MPP, Myelin P0 protein, Myelin peripheral protein, Myelin protein zero

    基因ID

    4359

    NCBI登录号

    NP_000521
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