MPZ 抗体
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北京 101111
Quick Overview for MPZ 抗体 (ABIN953494)
抗原
See all MPZ 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes P0 Myelin Protein.
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纯化方法
- Affinity Chromatography using a peptide column.
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免疫原
- Two antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (NP_032649) and Human (NP_000521) gene products. Production: After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.2 mg/ml. Finally, equal volumes of both of these affinity purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted in the dark at 2-8 °C.
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- MPZ (Myelin Protein Zero (MPZ))
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别名
- MPZ
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背景
- Human Myelin Protein Zero (Po) is a 28,400 dalton protein (258 amino acids) found in myelin of the PNS, but not the CNS. Expressed in myelinating Schwann cells, Po serves as a homophilic adhesion molecule, allowing adjacent laminae of the myelin sheath to undergo compaction. Po is also a marker of a subpopulation of migrating neural crest cells. Mutations of the MPZ gene product in humans is responsible for Charcot-Marie-Tooth type 1B neuropathies (HMSN1B).Synonyms: MPP, Myelin P0 protein, Myelin peripheral protein, Myelin protein zero
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基因ID
- 4359
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NCBI登录号
- NP_000521
抗原
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