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MHC Class I H-2KdDd 抗体 (Biotin)

The 小鼠 单克隆 anti-MHC Class I H-2KdDd antibody is suitable to detect MHC Class I H-2KdDd in samples from 小鼠. It has been validated for FACS.
产品编号 ABIN371168
发货至: 中国
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Quick Overview for MHC Class I H-2KdDd 抗体 (Biotin) (ABIN371168)

抗原

MHC Class I H-2KdDd

适用

小鼠

宿主

  • 4
小鼠

克隆类型

  • 4
单克隆

标记

  • 1
  • 1
  • 1
  • 1
Biotin

应用范围

  • 4
  • 4
  • 4
  • 4
Flow Cytometry (FACS)

克隆位点

34-1-2S
  • 纯化方法

    Protein G Chromatography

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    MHC Class I H-2KdDd

    别名

    MHC Class I H2 Kd/Dd

    背景

    The 'classical' MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant beta 2-Microglobulin. (Ref.3,4) These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. (Ref.5) MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny. (Ref.3,6)
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