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Melanophilin 抗体 (C-Term)

This anti-Melanophilin antibody is a 兔 多克隆 antibody detecting Melanophilin in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN953384
发货至: 中国

Quick Overview for Melanophilin 抗体 (C-Term) (ABIN953384)

抗原

See all Melanophilin (MLPH) 抗体
Melanophilin (MLPH)

适用

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宿主

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克隆类型

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多克隆

标记

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This Melanophilin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 540-569, C-Term

    特异性

    This antibody recognizes Melanophilin / MLPH at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Purified through a Protein A column followed by peptide affinity purification

    免疫原

    Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 540-569aa) of human Melanophilin.

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Melanophilin (MLPH)

    别名

    Melanophilin

    背景

    The MLPH gene encodes a member of the exophilin subfamily of Rab effector proteins, Melanophilin. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.Synonyms: Exophilin-3, Leaden protein, Ln, Mlph, Slac2a, Slp homolog lacking C2 domains a, Synaptotagmin-like protein 2a

    基因ID

    79083

    NCBI登录号

    NP_001035932
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