MED17 抗体 (Middle Region)
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北京 101111
Quick Overview for MED17 抗体 (Middle Region) (ABIN953370)
抗原
See all MED17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-361, Middle Region
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特异性
- This antibody recognizes Human MED17 (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 331-361 amino acids from the Central region of human MED17
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MED17 (Mediator Complex Subunit 17 (MED17))
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别名
- MED17
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背景
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.Synonyms: ARC77, Activator-recruited cofactor 77 kDa component, CRSP complex subunit 6, CRSP6, Cofactor required for Sp1 transcriptional activation subunit 6, DRIP77, DRIP80, Mediator complex subunit 17, Mediator of RNA polymerase II transcription subunit 17, TRAP80, Thyroid hormone receptor-associated protein complex 80 kDa component, Transcriptional coactivator CRSP77, Vitamin D3 receptor-interacting protein complex 80 kDa component
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分子量
- 72890 Da
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基因ID
- 9440
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NCBI登录号
- NP_004259
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
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