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Sca-1/Ly-6A/E 抗体

The 大鼠 单克隆 anti-Sca-1/Ly-6A/E antibody (Clone CT-6A-6E) (ABIN953250) specifically detects Sca-1/Ly-6A/E in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN953250
发货至: 中国
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Quick Overview for Sca-1/Ly-6A/E 抗体 (ABIN953250)

抗原

See all Sca-1/Ly-6A/E (Ly6a) 抗体
Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

适用

  • 61
  • 5
  • 2
小鼠

宿主

  • 34
  • 32
大鼠

克隆类型

  • 51
  • 15
单克隆

标记

  • 13
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Sca-1/Ly-6A/E antibody is un-conjugated

应用范围

  • 33
  • 22
  • 20
  • 11
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

CT-6A-6E
  • 特异性

    This monoclonal antibody recognizes Sca-1 (Ly-6A.2/6E.1), a cell surface antigen used in the identification of hematopoietic stem cells.

    纯化方法

    Affinity chromatography on Protein G

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide (NaN3) as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

    别名

    Ly6A/E / SCA1

    背景

    Ly6A/E is a member of the Ly-6 antigen family. The Thy-1lo, Lin- (lineage-negative, not expressing B220, Gr-1, Mac-1, CD4 or CD8), Sca-1+ population of bone marrow cells are highly purified, perhaps homogenous, pluripotent stem cells. This antigen is also present on various other tissues. Specific staining of the parenchymal cells can be demonstrated in thymus, spleen and kidney where as only vasculature reacts with anti-Sca-1 in brain, heart and liver (and possibly in lung). Also, Sca-1 is a T cell activation antigen, as surface expression of the antigen increases upon Con A activation of T lymphocytes. Sca-1 appears to have a molecular mass of 8 kDa under non-reducing conditions and 18 kDa under reducing conditions, indicating the presence of intra-chain disulfide bonds.Synonyms: Ly-6A.2/Ly-6E.1, Lymphocyte antigen 6A-2/6E-1, SCA-1, Stem cell antigen 1, T-cell-activating protein, TAP

    基因ID

    110454

    NCBI登录号

    NP_034868

    UniProt

    P05533

    途径

    Sensory Perception of Sound, Activated T Cell Proliferation
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