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KDM3B 抗体 (Middle Region)

This anti-KDM3B antibody is a 兔 多克隆 antibody detecting KDM3B in WB, FACS 和 EIA. Suitable for 人.
产品编号 ABIN952970
发货至: 中国

Quick Overview for KDM3B 抗体 (Middle Region) (ABIN952970)

抗原

See all KDM3B 抗体
KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

适用

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宿主

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克隆类型

  • 61
多克隆

标记

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This KDM3B antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 876-905, Middle Region

    特异性

    This antibody recognizes Human JMJD1B / KDM3B (Center).

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    免疫原

    KLH conjugated synthetic peptide between 876-905 amino acids from the Central region of human JHDM2b Genename: KDM3B

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

    别名

    JMJD1B / KDM3B

    背景

    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: 5qNCA, C5orf7, JHDM2B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, KIAA1082, Lysine-specific demethylase 3B, Nuclear protein 5qNCA

    分子量

    84kd

    基因ID

    51780

    NCBI登录号

    NP_057688

    途径

    Warburg Effect
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