IDH3G 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for IDH3G 抗体 (C-Term) (ABIN952962)
抗原
See all IDH3G 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 364-393, C-Term
-
特异性
- This antibody recognizes Human Isocitric dehydrogenase gamma / IDH3G (C-term).
-
纯化方法
- Protein A column, followed by peptide affinity purification
-
免疫原
- KLH conjugated synthetic peptide between 364~393 amino acids from the C-terminal region of human IDH3G
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))
-
别名
- Isocitric Dehydrogenase gamma / IDH3G
-
背景
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia.Synonyms: NAD(+)-specific ICDH gamma, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma
-
分子量
- 42794 Da
-
基因ID
- 3421
-
NCBI登录号
- NP_004126
抗原
-