INHBB 抗体 (C-Term)
Quick Overview for INHBB 抗体 (C-Term) (ABIN952903)
抗原
See all INHBB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 376-404, C-Term
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特异性
- This antibody recognizes Human and Mouse INHBB (C-term).
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产品特性
- Purified Ig fraction
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human INHBB
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亚型
- Ig Fraction
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应用备注
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Suggested dilutions:
ELISA: 1/1000.
Western Blot: 1/100-1/500.
Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy." in: Journal of cachexia, sarcopenia and muscle, Vol. 10, Issue 5, pp. 1083-1101, (2020) (PubMed).
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The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy." in: Journal of cachexia, sarcopenia and muscle, Vol. 10, Issue 5, pp. 1083-1101, (2020) (PubMed).
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- INHBB (Inhibin, beta B (INHBB))
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别名
- Inhibin beta B Chain (INHBB)
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背景
- The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.Synonyms: Activin B, Activin beta-B chain
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分子量
- 45122 Da
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基因ID
- 3625
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NCBI登录号
- NP_002184
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UniProt
- P09529
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途径
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
抗原
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