HYAL2 抗体 (C-Term)
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Quick Overview for HYAL2 抗体 (C-Term) (ABIN952809)
抗原
See all HYAL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 388-416, C-Term
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特异性
- This antibody recognizes Human HYAL2 / Hyaluronidase-2 (C-term).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 388-416 amino acids from the C-terminal region of human HYAL2 / Hyaluronidase-2
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HYAL2 (Hyaluronidase-2 (HYAL2))
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别名
- HYAL2 / Hyaluronidase-2
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背景
- This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.Synonyms: Hyal-2, Hyaluronoglucosaminidase-2, LUCA2, Lung carcinoma protein 2
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分子量
- 53860 Da
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基因ID
- 8692
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NCBI登录号
- NP_003764
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途径
- Transition Metal Ion Homeostasis, Glycosaminoglycan Metabolic Process
抗原
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