HAX1 抗体 (C-Term)
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Quick Overview for HAX1 抗体 (C-Term) (ABIN952684)
抗原
See all HAX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-190, C-Term
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特异性
- This antibody recognizes Human HAX1 (C-term).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 160-190 amino acids from the C-terminal region of Human HAX1.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
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别名
- HAX1
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背景
- The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1
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分子量
- 31621 Da
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基因ID
- 10456
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NCBI登录号
- NP_001018238
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途径
- Regulation of Actin Filament Polymerization
抗原
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