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Haptoglobin 抗体 (Middle Region)

This anti-Haptoglobin antibody is a 兔 多克隆 antibody detecting Haptoglobin in WB, FACS, IF, IHC (p) 和 EIA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN952678
发货至: 中国

Quick Overview for Haptoglobin 抗体 (Middle Region) (ABIN952678)

抗原

See all Haptoglobin (HP) 抗体
Haptoglobin (HP)

适用

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宿主

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克隆类型

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多克隆

标记

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This Haptoglobin antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    AA 299-326, Middle Region

    特异性

    This antibody recognizes Human Haptoglobin (Center).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 299-326 amino acids from the Central region of Human Haptoglobin Genename: HP

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Higham, Baker, Jackson, Shah, Lea, Singh: "Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients." in: Cells, Vol. 11, Issue 1, (2022) (PubMed).

  • 抗原

    Haptoglobin (HP)

    别名

    Haptoglobin

    背景

    This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    45205 Da

    基因ID

    3240

    NCBI登录号

    NP_001119574

    途径

    Transition Metal Ion Homeostasis
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