GPER 抗体 (C-Term)
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Quick Overview for GPER 抗体 (C-Term) (ABIN952589)
抗原
See all GPER 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 345-375, C-Term
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特异性
- This antibody reacts to GPER.
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交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of human GPER
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))
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别名
- GPER / GPR30
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背景
- This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq].Synonyms: CEPR, CMKRL2, Chemoattractant receptor-like 2, DRY12, FEG1, Flow-induced endothelial G-protein coupled receptor 1, G-protein coupled estrogen receptor 1, G-protein coupled receptor 30, GPCR-BR, IL8-related receptor DRY12, LYGPR, Lymphocyte-derived G-protein coupled receptor
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分子量
- 42248 Da
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基因ID
- 2852
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NCBI登录号
- NP_001035055
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途径
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
抗原
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