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- 抗原 See all GPC2 抗体
- GPC2 (Glypican 2 (GPC2))
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抗原表位
- AA 136-165, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- Recognizes GPC2 (N-term).
- 纯化方法
- Protein A column followed by peptide Affinity purification
- 免疫原
- KLH conjugated synthetic peptide between 136-165 amino acids from the N-terminal region of Human GPC2 (NP_689955.1) Genename: GPC2
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GPC2 Primary Antibody
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anti-Glypican 2 (GPC2) antibody
GPC2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glypican 2 (GPC2) (AA 137-165), (N-Term) antibodyGPC2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- GPC2 (Glypican 2 (GPC2))
- 别名
- GPC2 (GPC2 产品)
- 背景
- The glypicans (GPC) constitute a family of heparan sulfate proteoglycans that are attached to the cell surface by a lycosylphosphatidylinositol (GPI) anchor. Six members of this family have been identified in mammals (GPC1-GPC6). All glypican core proteins contain an N-terminal signal peptide, a large globular cysteine rich domain (CRD) with 14 invariant cysteine residues, a stalklike region containing the heparan sulfate attachment sites, and a C-terminal GPI attachment site. Based on the degree of their amino acid sequence similarity, two subfamilies of glypicans have been defined. One subfamily (sharing from 35-63 % sequence homology) includes GPC1, 2, 4, and 6, while the second subfamily (sharing 54 % sequence identity) includes GPC3 and 5. Proteins between the two subfamilies also share 17-25 % sequence similarity (1-4). Glypicans are widely expressed in adult and fetal tissues. During embryonic development, the expression level of the various glypicans changes in a stage and tissue specific manner. GPC2, also known as cerebroglycan, is primarily expressed in developing neuronal tissues including the brain, spinal cord, dorsal root ganglia, and cranial nerves. It is found on the tracts of actively growing axons (5). Cell surface GPC2 binds midkine, indicating midkine GPC2 interaction may participate in neuronal cell migration and neurite outgrowth (6).Synonyms: Glypican-2
- 基因ID
- 221914
- NCBI登录号
- NP_689955
- 途径
- Glycosaminoglycan Metabolic Process
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