GNAS 抗体 (C-Term)
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北京 101111
Quick Overview for GNAS 抗体 (C-Term) (ABIN952563)
抗原
See all GNAS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 286-315, C-Term
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 286-315 amino acids from the C-terminal region of Human GNAS
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亚型
- Ig Fraction
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anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A2B7 unconjugated
anti-GNAS Complex Locus (GNAS) (N-Term) antibodyGNAS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) antibodyKO Validated GNAS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 42-188) antibodyGNAS 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G6G5 unconjugated
anti-GNAS Complex Locus (GNAS) (N-Term) antibodyGNAS 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 1-394) antibodyGNAS 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 310-404) antibodyGNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (Internal Region) antibodyVerified GNAS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 287-315), (C-Term) antibodyGNAS 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33001 unconjugated
anti-GNAS Complex Locus (GNAS) (AA 1-394) antibodyGNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GNAS (GNAS Complex Locus (GNAS))
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别名
- GNAS
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背景
- Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
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分子量
- 44,250 Da
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基因ID
- 9606
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途径
- Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
抗原
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