GLIS2 抗体 (Middle Region)
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Quick Overview for GLIS2 抗体 (Middle Region) (ABIN952526)
抗原
See all GLIS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 172-202, Middle Region
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特异性
- This antibody recognizes Human GLIS2 (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 172-202 amino acids from the Central region of Human GLIS2.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
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别名
- GLIS2
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背景
- This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.Synonyms: GLI-similar 2, NKL, Neuronal Krueppel-like protein, Zinc finger protein GLIS2
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分子量
- 55689 Da
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基因ID
- 84662
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NCBI登录号
- NP_115964
抗原
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