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GLIS2 抗体 (Middle Region)

This anti-GLIS2 antibody is a 兔 多克隆 antibody detecting GLIS2 in WB 和 EIA. Suitable for 人.
产品编号 ABIN952526
发货至: 中国

Quick Overview for GLIS2 抗体 (Middle Region) (ABIN952526)

抗原

See all GLIS2 抗体
GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

适用

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宿主

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克隆类型

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多克隆

标记

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This GLIS2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 172-202, Middle Region

    特异性

    This antibody recognizes Human GLIS2 (Center).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 172-202 amino acids from the Central region of Human GLIS2.

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

    别名

    GLIS2

    背景

    This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.Synonyms: GLI-similar 2, NKL, Neuronal Krueppel-like protein, Zinc finger protein GLIS2

    分子量

    55689 Da

    基因ID

    84662

    NCBI登录号

    NP_115964
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