GRPR 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for GRPR 抗体 (Middle Region) (ABIN952465)
抗原
See all GRPR 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 130-160, Middle Region
-
特异性
- This antibody recognizes Human Gastrin-releasing peptide receptor (Center).
-
纯化方法
- Protein A column, followed by peptide affinity purification
-
免疫原
- KLH conjugated synthetic peptide between 130~160 amino acids from the Central region of Human Gastrin-releasing peptide receptor Genename: GRPR
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
-
别名
- Gastrin-Releasing Peptide Receptor
-
背景
- Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.Synonyms: GRP-R, GRP-preferring bombesin receptor, GRPR
-
分子量
- 43199 Da
-
基因ID
- 2925
-
NCBI登录号
- NP_005305
抗原
-