CRYGB 抗体 (Middle Region)
Quick Overview for CRYGB 抗体 (Middle Region) (ABIN952455)
抗原
See all CRYGB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 67-97, Middle Region
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特异性
- This antibody recognizes Human Gamma-crystallin B (Center).
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 67-97 amino acids from the Central region of Human CRYGB. Genename: CRYGB
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亚型
- Ig Fraction
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anti-Crystallin, gamma B (CRYGB) (AA 80-135) antibody
CRYGB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, gamma B (CRYGB) antibodyCRYGB 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, gamma B (CRYGB) (AA 68-97) antibodyCRYGB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CRYGB (Crystallin, gamma B (CRYGB))
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别名
- gamma-Crystallin B
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背景
- Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.Synonyms: CRYG2, CRYGB, Gamma-B-crystallin, Gamma-crystallin 1-2
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基因ID
- 1419
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NCBI登录号
- NP_005201
抗原
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