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FBXO4 抗体 (Middle Region)

This anti-FBXO4 antibody is a 兔 多克隆 antibody detecting FBXO4 in WB 和 EIA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN952288
发货至: 中国

Quick Overview for FBXO4 抗体 (Middle Region) (ABIN952288)

抗原

See all FBXO4 抗体
FBXO4 (F-Box Protein 4 (FBXO4))

适用

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宿主

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克隆类型

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多克隆

标记

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This FBXO4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 231-260, Middle Region

    特异性

    This antibody recognizes Human FBXO4 (Center).

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 231~260 amino acids from the Center region of human FBXO4

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Barbash, Zamfirova, Lin, Chen, Yang, Nakagawa, Lu, Rustgi, Diehl: "Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer." in: Cancer cell, Vol. 14, Issue 1, pp. 68-78, (2008) (PubMed).

  • 抗原

    FBXO4 (F-Box Protein 4 (FBXO4))

    别名

    FBXO4

    背景

    FBXO4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class.Synonyms: F-box only protein 4, FBX4

    分子量

    44136 Da

    基因ID

    26272

    NCBI登录号

    NP_036308
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