EPOR 抗体 (Middle Region)
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北京 101111
Quick Overview for EPOR 抗体 (Middle Region) (ABIN952118)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 328-357, Middle Region
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特异性
- This antibody recognizes Human Erythropoietin receptor (Center).
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 328-357 amino acids from the Central region of Human Erythropoietin receptor Genename: EPOR
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- EPOR (Erythropoietin Receptor (EPOR))
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别名
- Erythropoietin Receptor
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背景
- This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.Synonyms: EPO-R, EPOR
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分子量
- 55065 Da
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基因ID
- 2057
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NCBI登录号
- NP_000112
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途径
- JAK/STAT Signaling
抗原
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