ERI1 抗体 (N-Term)
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Quick Overview for ERI1 抗体 (N-Term) (ABIN952107)
抗原
See all ERI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 79-109, N-Term
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特异性
- This antibody recognizes Human ERI1 / THEX1 (N-term).
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of Human ERI1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ERI1 (Exoribonuclease 1 (ERI1))
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别名
- ERI1 / THEX1
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背景
- RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.Synonyms: 3'-5' exonuclease ERI1, 3'-5' exoribonuclease 1, 3'EXO, Eri-1 homolog, HEXO, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo
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分子量
- 40064 Da
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基因ID
- 90459
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NCBI登录号
- NP_699163
抗原
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