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ERI1 抗体 (N-Term)

This anti-ERI1 antibody is a 兔 多克隆 antibody detecting ERI1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN952107
发货至: 中国

Quick Overview for ERI1 抗体 (N-Term) (ABIN952107)

抗原

See all ERI1 抗体
ERI1 (Exoribonuclease 1 (ERI1))

适用

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宿主

  • 58
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克隆类型

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多克隆

标记

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This ERI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 79-109, N-Term

    特异性

    This antibody recognizes Human ERI1 / THEX1 (N-term).

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of Human ERI1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ERI1 (Exoribonuclease 1 (ERI1))

    别名

    ERI1 / THEX1

    背景

    RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.Synonyms: 3'-5' exonuclease ERI1, 3'-5' exoribonuclease 1, 3'EXO, Eri-1 homolog, HEXO, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo

    分子量

    40064 Da

    基因ID

    90459

    NCBI登录号

    NP_699163
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