EMILIN2 抗体
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Quick Overview for EMILIN2 抗体 (ABIN952078)
抗原
See all EMILIN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody was selected for its ability to detect Human Emilin-2.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Recombinant protein gC1q domain of EMILIN-2.
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Centrifuge vial prior to opening. Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for at least 6 months.
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有效期
- 6 months
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- EMILIN2 (Elastin Microfibril Interfacer 2 (EMILIN2))
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别名
- EMILIN2
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背景
- Emilins (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine-rich EMI domain and a conserved C-terminal gC1q-like domain. Emilin-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as Emilin-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as Emilin-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. Emilin-5 is encoded by the Emilin-3 gene and is sometimes referred to as Emilin-3. It contains the N-terminal cysteine-rich EMI domain but lacks the C-terminal gC1q-like domain. Emilin-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development.Synonyms: EMILIN-2, Elastin microfibril interface-located protein 2, Elastin microfibril interfacer 2, Protein FOAP-10
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基因ID
- 84034
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NCBI登录号
- NP_114437
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UniProt
- Q9BXX0
抗原
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